KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CNOT3
All Species:
21.82
Human Site:
S263
Identified Species:
48
UniProt:
O75175
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75175
NP_055331.1
753
81872
S263
Q
S
S
S
T
P
T
S
T
T
S
S
S
P
I
Chimpanzee
Pan troglodytes
XP_512885
688
76993
R201
S
I
L
V
D
A
I
R
K
I
K
D
D
V
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541428
752
81536
S263
Q
S
S
S
T
P
T
S
T
T
S
S
S
P
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0V4
751
81927
S263
Q
S
S
S
T
P
T
S
T
T
S
S
S
P
I
Rat
Rattus norvegicus
NP_001100941
751
81862
S263
Q
S
S
S
T
P
T
S
T
T
S
S
S
P
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086992
728
81088
T238
D
L
D
D
I
P
Q
T
G
V
A
A
S
P
P
Zebra Danio
Brachydanio rerio
NP_956134
908
96903
T263
S
S
T
P
T
S
T
T
S
S
S
P
I
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610176
844
92349
S267
S
S
V
T
S
G
G
S
P
S
Q
S
P
V
T
Honey Bee
Apis mellifera
XP_395261
684
76726
N197
D
N
M
S
V
E
V
N
T
I
K
R
I
K
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203995
878
98224
S263
I
S
P
I
V
S
S
S
L
P
S
T
S
N
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06102
836
94385
Q264
S
D
A
N
E
S
L
Q
D
I
S
K
L
S
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.9
N.A.
96.6
N.A.
95.2
95.4
N.A.
N.A.
N.A.
77.1
54.2
N.A.
41.5
51.9
N.A.
45.3
Protein Similarity:
100
88.1
N.A.
97.6
N.A.
96.4
96.6
N.A.
N.A.
N.A.
84
63.9
N.A.
57.7
65.7
N.A.
58.5
P-Site Identity:
100
0
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
20
33.3
N.A.
20
13.3
N.A.
26.6
P-Site Similarity:
100
0
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
40
60
N.A.
40
26.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
10
0
0
0
0
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
10
10
10
10
0
0
0
10
0
0
10
10
0
10
% D
% Glu:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
10
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
10
10
0
10
10
0
10
0
0
28
0
0
19
0
37
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
19
10
0
10
10
% K
% Leu:
0
10
10
0
0
0
10
0
10
0
0
0
10
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
0
0
0
10
0
0
0
0
0
10
0
% N
% Pro:
0
0
10
10
0
46
0
0
10
10
0
10
10
55
19
% P
% Gln:
37
0
0
0
0
0
10
10
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% R
% Ser:
37
64
37
46
10
28
10
55
10
19
64
46
55
10
0
% S
% Thr:
0
0
10
10
46
0
46
19
46
37
0
10
0
0
10
% T
% Val:
0
0
10
10
19
0
10
0
0
10
0
0
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _